Journal article
Enhanced wireless cell stimulation using soft and improved bipolar electroactive conducting polymer templates
Chunyan Qin, Zhilian Yue, Xu-Feng Huang, Robert J Forster, Gordon G Wallace, Jun Chen
APPLIED MATERIALS TODAY | ELSEVIER | Published : 2022
Abstract
Bipolar electrostimulation (BPES) invoked using organic conducting polymers (CPs) has provided a unique route to communicating with living cells. This work brings new dimensions to BPES in terms of the conducting polymer composition and the ability to implement on a soft substrate. Poly(2-methoxyaniline-5-sulfonic acid) (PMAS) has been used as a redox active, electronically conductive dopant to enhance the electrochemical properties of the host polypyrrole (PPy). Significantly, rat PC 12 cells cultivated on a multilayer, mechanically flexible, conducting polymer support show increased differentiation when BPES is applied. The soft template (PPy-PMAS-collagen/PEDOT-PSS) comprises poly(3,4-eth..
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Awarded by Australian Research Council (ARC) Centre of Excellence Scheme
Funding Acknowledgements
This work was financially supported by the funding from the Australian Research Council (ARC) Centre of Excellence Scheme (CE140100 012). The authors wish to acknowledge the support of facilities at the University of Wollongong Electron Microscopy Centre (EMC), support from the Australian National Fabrication Facility (ANFF)-Materials Node, Dr Gregory Ryder for help with PMAS synthesis and Dr Patricia Hayes for support with spectra measurements.